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Navigating Upper Tract Urothelial Carcinoma

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In this episode, Dr. Jose Silva speaks with Dr. Padraic O’Malley, urologic oncologist at the University of Florida Health, about the diagnosis and management of upper tract urothelial carcinoma (UTUC). The discussion integrates current guidelines with clinical experience to explore treatment options such as tumor ablation, JELMYTO, neoadjuvant chemotherapy, and nephroureterectomy. The experts also review the role of lymph node dissection, the implications of Lynch syndrome, and evolving technologies such as the Thulium laser, concluding with insights on follow-up care and the need for standardized reporting and risk stratification.

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Contributors:

Dr. Padraic O’Malley is an associate professor and the chief of urologic oncology at University of Florida in Gainesville.

Dr. Jose Silva is a board certified urologist practicing in Central Florida.